期刊發表

歷年發表的論文：
 

 

發表年份	題名及簡述	刊名(卷號)
2023	Para-toluenesulfonamide, a novel potent carbonic anhydrase inhibitor, improves hypoxia-induced metastatic breast cancer cell viability and prevents resistance to αPD-1 therapy in triple-negative breast cancer PTS為CA9抑制劑，改善腫瘤微環境，加強免疫檢查點藥物合併療效	Biomedicine & Pharmacotherapy Volume 167, November 2023, 115533
2022	Effects of Para-Toluenesulfonamide on Canine Melanoma Xenotransplants in a BALB/c Nude Mouse Model PTS試驗藥品對犬黑色素瘤抑制效果	Animals 2022, 12(17), 2272
2021	Autophagic Activation and Decrease of Plasma Membrane Cholesterol Contribute to Anticancer Activities in Non-Small Cell Lung Cancer PTS在非小細胞肺癌中，透過活化細胞自噬作用及減少細胞膜上膽固醇，達成抗腫瘤活性	Molecules. 2021 Oct 1;26(19):5967
2018	Effects of para-toluenesulfonamide intratumoral injection on pulmonary adenoid cystic carcinoma complicating with severe central airway obstruction: a 5-year follow-up study 瘤內注射對甲苯磺酰胺治療肺部腺樣囊性癌合併嚴重中央氣道阻塞：5年隨訪研究	J Thorac Dis. 2018 Apr;10(4):2448-2455.
2018	Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and –Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents 對甲苯磺酰胺通過Akt依賴性和非依賴性mTOR / p70S6K途徑誘導抗腫瘤活性：對脂筏和膽固醇含量的作用	Front Pharmacol. 2018 Nov 13;9:1223.
2016	Effects of para–toluenesulfonamide intratumoral injection on non-small cell lung carcinoma with severe central airway obstruction: A multi-center, non-randomized, single-arm, open-label trial 瘤內注射對甲苯磺酰胺治療患有嚴重中央氣道阻塞的非小細胞肺癌：一項多中心，非隨機，單臂，開放性試驗	Lung Cancer. 2016 Aug;98:43-50.
2015	Para-toluenesulfonamide induces tongue squamous cell carcinoma cell death through disturbing lysosomal stability 對甲苯磺酰胺通過破壞溶酶體穩定性誘導舌鱗狀細胞癌細胞死亡	Anticancer Drugs . 2015 Nov;26(10):1026-33
2013	Antitumor effect of para-toluenesulfonamide against lung cancer xenograft in a mouse model 對甲苯磺酰胺對大鼠移植肺癌的治療作用	J Thorac Dis 2013;5(4):472-483.
2012	Puncture injection of para-toluenesulfonamide combined with chemoembolization for advanced hepatocellular carcinoma 穿刺注射對甲苯磺酰胺聯合化學栓塞治療晚期肝細胞癌	World J Gastroenterol. 2012 Dec 14;18(46):6861-4.
2006	Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies 體內和體外研究對甲苯磺酰胺的代謝及其對大鼠肝微粒體細胞色素P450的影響	Acta Pharmacol Sin. 2006 May;27(5):635-40.
2006	An evaluation of para toluene-sulfonamide metabolism and effect with regard to CYP isoforms, P-glycoprotein, and drug interactions 對甲苯磺酰胺的代謝及其對CYP亞型，P-糖蛋白和藥物相互作用的影響評估	Pharmazie. 2006 Oct;61(10):869-73.